What is Metabolic Syndrome?
There are several diseases and multiple combinations of those diseases that can comprise metabolic syndrome. The main three are Pituitary Pars Intermidia Dysfunction (Cushings disease), Type II Diabetes/Insulin Resistance, and Hhypothyroidism. They can occur individually or in combination with each other.
First let me give you some background information on each disease separately.
Pituitary Pars Intermedia Dysfunction (Cushing’s Disease):
This is caused by a cortisol secreting tumor called a pituitary ademona. The tumor is very small and in general will never grow to a size large enough to cause any significant “brain tumor” issues. However, this tiny tumor causes major havoc with the rest of the body. Cortisol acts on the horse’s other systems by increasing weight gain, producing a classic long, shaggy hair coat throughout the year, raising the horse’s internal body temperature, and increasing the horse’s risk of founder. The disease can be treated successfully using either Pergolide or Cyproheptidine, with pergolide being the most common and the most effective in the majority of cases. We test for PPID using one or a combination of the following blood tests: Dexamethasone suppression test, Endogenous AcTH levels, TSH levels, and resting cortisol levels. Once a diagnosis has been made for this disease and treatment has been initiated, the horse’s progress and drug dosages are usually monitored via one or two of these tests.
Type II Diabetes/Insulin Resistance
We appologize, this article is still under construction….